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Cortisol, Urine Free by LC-MS/MS

Mnemonic:    [U CORTISOL]
Name:    Cortisol, Urine Free by LC-MS/MS
Specimen:    4 mL aliquot from a 24 hour or random urine collection.
Refrigerate 24-hour sample during collection.

Unacceptable Conditions: Room temperature specimens. Acidified specimens or specimens with preservatives.
Transport Temp:    Refrigerated
Spec Stability:    Stable up to 2 weeks refrigerated.
Ref Lab/Code:    ARUP 0097222
  Method:    Liquid Chromatography/Tandem Mass Spectrometry
Note:    Interpretive Data: Ratios to creatinine may be useful for evaluation when the urine collection is random, other than 24 hours, or the urine volume is less than 400 mL/24 hours. Low urinary cortisol concentrations may be consistent with adrenal insufficiency.
Processing Info:    Record total volume and collection time interval on transport tube and on packing list. Have a tech verify the SR TIME and SR VOLUME before the packing list is transmitted.