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D-Dimer

Mnemonic:    [D Dimer]
Name:    D-Dimer
Specimen:    2 mL plasma from a FULL sodium citrate Blue top tube. Allow tube to fill to proper capacity. Mix immediately by gentle inversion 4 times. Room temperature sample must be delivered to the CMMC hematology lab within one hour of collection. If the unspun sample cannot be delivered to the lab in that time period, the patient should be sent to the CMMC Outpatient Phlebotomy area for specimen collection.

A D-dimer can be added to an existing sample up to 8 hours after collection, if it was spun within one hour of collection and the container has not been opened for previous testing. If the tube has been previously opened, the sample is only good for 4 hours from the time it was opened.
Minimum Spec:    0.5 mL
Reference Range:    < 0.45 uG/mL (FEU)
  Method:    Immuno-Turbidimetric Assay
Note:    Deep venous thrombosis/pulmonary embolus (DVT/PE) is highly unlikely in a patient with a negative D-Dimer (less than 0.45 ug/mL FEU) and a low-to-moderate risk of DVT/PE (Wells score below 2).

A positive D-Dimer (greater than 0.45 ug/mL) can be seen in pregnancy and puerperium, in the elderly, and in patients with recent surgery, trauma, infection, atherosclerosis, cancer, liver disease, disseminated intravascular coagulation (DIC) or DVT/PE.
Processing Info:    The sample must be kept at room temperature prior to centrifugation. Any samples received separated must have been processed in a CAP approved calibrated and documented centrifuge to provide platelet poor plasma.