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Catecholamines Fractionated, Plasma

Mnemonic:    [CATECHOL]
Name:    Catecholamines Fractionated, Plasma
Specimen:    4 mL plasma from a Green PST. Patient should be calm AND in a supine position for 30 minutes prior to collection.

Collect the sample on ice. Centrifuge the sample to separate the plasma from cells within 1 hour of collection. A refrigerated centrifuge is preferred but not required.

Unacceptable Conditions: EDTA plasma, serum, or urine.
Minimum Spec:    2.5 mL
Transport Temp:    FREEZE
Ref Lab/Code:    ARUP 0080216
  Method:    High Performance Liquid Chromatography (HPLC)
Note:    Includes: Dopamine, Epinephrine, and Norepinephrine.

Medications which may interfere with catecholamines and metabolites include amphetamines and amphetamine-like compounds, appetite suppressants, bromocriptine, buspirone, caffeine, carbidopa-levodopa (Sinemet), clonidine, dexamethasone, diuretics (in doses sufficient to deplete sodium), ethanol, isoproterenol, labetalol, methyldopa (Aldomet), MAO inhibitors, nicotine, nose drops, propafenone (Rythmol), reserpine, theophylline, tricyclic antidepressants, and vasodilators. The effects of drugs on catecholamine results may not be predictable.