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Maternal Serum Screen, Integrated, Specimen #1

Mnemonic:    [MS INT-1]
Name:    Maternal Serum Screen, Integrated, Specimen #1
Specimen:    1 mL serum from a Red SST or Red top tube. Separate serum from cells ASAP.

The nuchal translucency (NT) measurement is preferred; however, the Integrated Maternal Screen can be interpreted with or without a NT measurement. If performed, the NT measurement must be obtained between 10 weeks, 3 days and 13 weeks, 6 days gestation (Crown-Rump length (CRL) must be 3.6-8.5 cm). The NT measurement must also be performed by an ultrasonographer that is certified by one of the following agencies: Fetal Medicine Foundation (FMF) or Nuchal Translucency Quality Review (NTQR). To avoid possible test delays for an ultrasonographer that is new to our database, please contact the genetic counselor at (800) 242-2787 extension 2141 prior to sending specimen.

Serum-only specimens may be drawn between 10 weeks, 0 days and 13 weeks, 6 days gestation. Crown-Rump length (CRL) must be 3.2-8.5 cm. The specimen collection and ultrasound date may be different.

Minimum Spec:    0.3 mL
Transport Temp:    Refrigerated
Spec Stability:    Stable up to 2 weeks refrigerated.
Ref Lab/Code:    ARUP 0081062
  Method:    Chemiluminescent Immunoassay
Note:    Screening test for DS, T18, and ONTD. Risks determined using a combination of 1st and 2nd trimester serum markers, with or without 1st trimester nuchal translucency (NT) measurement. Results require a second sample between 15 and 24 weeks gestation (Maternal Serum Screening, Integrated, Specimen #2 0081064).

The first specimen of an Integrated Maternal Serum Screening is used to measure PAPP-A. Final interpretative report will be available when the second specimen test results are complete.
Processing Info:    Submit completed Patient History Form to ARUP with Sample.

Patient History Maternal Serum Testing ARUP