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Autoimmune Neuromuscular Junction Reflex Panel

Mnemonic:    [MusWeak Panel]
Name:    Autoimmune Neuromuscular Junction Reflex Panel
Specimen:    2 mL serum from a Red SST or Red top tube. Separate serum from cells within one hour. Unacceptable: plasma, hemolyzed or grossly lipemic samples.
Minimum Spec:    1 mL
Transport Temp:    Refrigerated
Spec Stability:    Stable up to 2 weeks refrigerated.
Ref Lab/Code:    ARUP 2005640
  Method:    Multi-Analyte Fluorescence Detection
Note:    This panel was previously named: Muscle Weakness Autoimmune Reflex Panel.

This is an acceptable reflexive panel for the differential diagnosis of acquired neuromuscular junction disorders. Panel contains binding, blocking, and modulating antibodies; voltage-gated calcium and potassium channels; titin antibody; and striated muscle antibodies.

Note: If Acetylcholine Receptor Binding Antibody result is greater than 0.4 nmol/L or Acetylcholine Receptor Blocking Antibody result is greater than 26 percent, then Acetylcholine Receptor Modulating Antibody will be added. If Striated Muscle Ab is detected, then a titer will be added. If VGKC is Indeterminate or Positive, LGI1 Antibody IgG and CASPR2 Antibody IgG will be added. If LGI1 antibody IgG is positive, then LGI1 antibody IgG titer will be added. If CASPR2 antibody IgG is positive, then CASPR2 antibody IgG titer will be added. Additional charges apply.