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Chromosome FISH, Multiple Myeloma (MM) Panel

Mnemonic:    [ChrFISH MM]
Name:    Chromosome FISH, Multiple Myeloma (MM) Panel
Specimen:    3 mL Bone Marrow aspirate collected in a heparinized syring and transferred to a green sodium heparin tube
Whole blood in 1 10 mL green (sodium heparin with no gel) is also acceptable if there are >20% blast cells.

Keep sample at room temperature.

Refrigerated and frozen samples are unacceptable.
Minimum Spec:    1 mL
Transport Temp:    Store and transport sample at Room Temperature.
Spec Stability:    Stable 24 hours ambient.
Ref Lab/Code:    ARUP 2002294
  Method:    Fluorescence in situ Hybridization
Note:    Fluorescence in situ hybridization (FISH) panel is performed for multiple myeloma prognosis specific genomic abnormalities as follows:

1. IGH/CCND1 t(11;14),
2. D13S319 deletion 13
3. IgH rearrangement,
4. TP53 deletion 17

Remarks: It is recommended that all FISH studies be done in conjunction with routine cytogenetic analysis. (Refer to appropriate Chromosome Analysis test for order instructions). If FISH only is requested, please include copy of previous cytogenetics report. If dropped cytogenetics slides or cell pellets are not submitted, a processing fee will apply.
Processing Info:    
This test is not orderable in Powerchart. Send the request on a Downtime or Manual Requisition.

ARUP's Cytogenetics Patient History Form