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Zollinger-Ellison Syndrome Testing - Gastrinoma

Mnemonic:     
Name:    Zollinger-Ellison Syndrome Testing - Gastrinoma
Specimen:     See ARUP Consult for testing algorithm:

http://www.arupconsult.com/Topics/OncologicDz/NeuroendocrineTumors/Gastrinoma.html

Initial testing consists of a fasting gastrin level and a gastric pH. If these results not diagnostic, a Secretin Stimulation Test may be indicated where timed gastrin levels are drawn after secretin stimulation is performed.

Timing and proper specimen processing are critical (see Gastrin Level for sample processing instructions after reviewing the diagnosis and algorithm on ARUP lab's website)
Note:    
Indications for testing: recurrent ulcers, diarrhea, gastroesophageal reflux disease (GERD)