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BCR-ABL1, Qualitative with reflex to BCR-ABL1 Quantitative

Mnemonic:    [BCRABL R]
Name:    BCR-ABL1, Qualitative with reflex to BCR-ABL1 Quantitative
Specimen:    5 mL whole blood from a Lavender top tube.
Test can be performed also on 3 mL of bone marrow.

Write on the tube "peripheral blood" or "bone marrow".

Collect sample in the AM to make the noon courier run. The sample must reach the reference lab within 48 hours.

Serum or plasma is unacceptable. Clotted or frozen samples are unacceptable.
Minimum Spec:    1 mL
Transport Temp:    Refrigerated
Spec Stability:    Stable 2 days refrigerated.
Ref Lab/Code:    ARUP 2005010
  Method:    RT PCR/Fluoresence Monitoring
Note:    This reflex assay is recommended when the BCR-ABL1 fusion form is not known or unclear. This reflex assay detects the presence of either the p210 (major breakpoint) or p190 (minor breakpoint). If the presence of either the p210 or p190 BCR-ABL1 fusion is detected, then the appropriate quantitative test will be performed.

If the fusion form is known, refer to BCR-ABL1, Major (p210), Quantitative (ARUP test code 2005017) or BCR-ABL1, Minor (p190), Quantitative (ARUP test code 2005016).