Clinical Research Projects Cancer

For more information regarding these studies, please contact Tracy Ackley at #795-7549 or 795-2935.

CENTRAL MAINE MEDICAL CENTER
COMPREHENSIVE CANCER PROGRAM

ONCOLOGY CLINICAL TRIALS

October 2008

BREAST

CALGB 40101

Cyclophosphamide and Doxorubicin (CA) (4 vs. 6 cycles) versus Paclitaxel (4 vs 6 cycles) as Adjuvant Therapy for Women with Node-Negative Breast Cancer:  A 2x2 Factorial Phase III Randomized Study.

SWOG S0226
Phase III Randomized Trial of Anastrozole Versus Anastrozole and Fulvestrant as First Line Therapy for Post Menopausal Women with Metastatic Breast Cancer

IBCSG 25-02 ENROLLMENT SUSPENDED
A Phase III Trial of Evaluating the Role of Exemestane Plus GnRH Analogue as Adjuvant Therapy for Premenopausal Women with Endocrine Responsive Breast Cancer

NSABP B-39/RTOG 0413
A Randomized Phase III Study of Conventional Whole Breast Irradiation (WBI) Versus Partial Breast Irradiation (PBI) for Women with Stage 0, I, or II Breast Cancer

NSABP B-42
A Clinical Trial to Determine the Efficacy of Five Years of Letrozole Compared to Placebo in Patients Completing Five Years of Hormonal Therapy Consisting of an Aromatase Inhibitor (AI) or tamoxifen Followed by an AI in Prolonging Disease-Free Survival in Postmenopausal Women with Hormone Receptor Positive Breast Cancer

PACCT-1
Program for the Assessment of Clinical Cancer Tests (PACCT-1): Trial Assigning Individualized Options for Treatment: The TAILORx Trial

BLADDER

CANCER CONTROL

GASTROINTESTINAL

CALGB 80101
Phase III Intergroup Trial of Adjuvant Chemoradiation After Resection of Gastric or Gastroesophageal Adenocarcinoma

CALGB 80405 ENROLLMENT SUSPENDED
A Phase III Trial of Irinotecan/5-FU/Leucovorin or Oxaliplatin/5-FU/Leucovorin with Bevacizumab, or Cetuximab (C225), or with the Combination of Bevacizumab and Cetuximab for Patients with Untreated Metastatic Adenocarcinoma of the Colon or Rectum

RTOG 0822
A Phase II Evaluation of Preoperative Chemoradiotherapy Utilizing Intensity Modulated Radiation Therapy (IMRT) in Combination With Capecitabine and Oxaloplatin for Patients With Locally Advanced Rectal Cancer

GYN

LEUKEMIA

CALGB 9665
The CALGB Leukemia Tissue Bank--(Laboratory Companion Study)

CALGB 8461
Cytogenetic Studies in Acute Leukemia--(Laboratory Companion Study)

CALGB 10105
A Phase II Study of an Oral VEGF Receptor Tyrosine Kinase Inhibitor (PTK787/ZK 222584) (IND# 66370, NSC# 719335) in Myelodysplastic Syndrome (MDS)

LYMPHOMA

MELANOMA

PROSTATE

CALGB 90202
A Randomized Double-Blind, Placebo-Controlled Phase III Study of Early Versus Standard Zoledronic Acid to Prevent Skeletal Related Events in Men with Prostate Cancer Metastatic to Bone

 RTOG 0534
A Phase III Trial of Short Term Androgen Deprivation With pelvic Lymph Node or Prostate Bed Only Radiotherapy (SPORT) in Prostate Cancer Patients With a Rising PSA After Radical Prostatectomy

RESPIRATORY

SWOG 0424
Molecular Epidemiology Case-Series Study of Non-Small Cell Lung Cancer in Smoking and Non-Smoking Women and Men

ECOG 1505
A Phase III Randomized Trial of Adjuvant Chemotherapy With or Without Bevacizumab for Patients With Completely Resected Stage IB (> 4 cm) – IIIA Non-Small Cell Lung Cancer (NSCLC)

RTOG 0617
A Randomized Phase III Comparison of Standard-Dose (60 Gy) Versus High-Dose (74 Gy0 Conformal Radiotherapy With Concurrent and Consolidation Carboplatin/Paclitaxel in Patients With Stage IIIA/IIIB Non-Small Cell Lung Cancer

SYMPTOM CONTROL

 

 

 

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