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Theophylline (Aminophylline) Level

Mnemonic:    [THEO]
Name:    Theophylline (Aminophylline) Level
Specimen:    1 mL serum from a Red SST or Red top tube, or plasma from a Green PST.
Spec Stability:    Stable 24 hours refrigerated.
Reference Range:    10 - 20 ug/mL
Critical Range:    > 30 ug/mL
  Method:    Alk Phos Inhibiting
Note:    For suspected toxicity, collect specimen anytime. For routine monitoring of orally administered therapy, specimen should be collected prior to the next dose. Peak levels are achieved after approx. 1 hour following short release drug, and approximately 4 hours after slow release preparations.