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Valproic Acid (Depakene/Depakote) Level

Mnemonic:    [VALPROIC]
Name:    Valproic Acid (Depakene/Depakote) Level
Specimen:    1 mL serum from a Red SST or Red top tube, or plasma from a Green PST.
Spec Stability:    Stable 5 days refrigerated.
Reference Range:    50 - 100 ug/mL
Critical Range:    > 120 ug/mL
  Method:    Enzymatic Homogeneous Competitive Immunoassay
Note:    For suspected toxicity, collect specimen anytime. For routine monitoring of orally administered therapy, specimen should be collected prior to the next dose. Peak levels are achieved after approx. 1-4 hours after ingestion.