Our Expertise - Research

CMMC Cancer Center Active in Research

The Central Maine Comprehensive Cancer Center places great emphasis on research for two reasons: to help our patients with cancer, and also to add to the knowledge base of the disease.

CMMC has a clinical research coordinator who monitors developments in cancer treatment and who works with patients and physicians to find the safest and most effective treatment for cancer patients.

CMMC also records and tracks all cancer cases diagnosed and treated here. The information is shared with other cancer researchers.

OPEN ONCOLOGY CLINICAL TRIALS

BREAST

NSABP B-43: A Phase III Clinical Trial Comparing Trastuzumab Given Concurrently with Radiation Therapy and Radiation Therapy Alone for Women with HER2-Positive Ductal Carcinoma In Situ Resected by Lumpectomy

NSABP B-39: A Randomized Phase III Study of Conventional Breast Irradiation (WBI) vs. Partial Breast Irradiation for Women with Stage 0, I, or II Breast Cancer

BRAIN

WFU91105: Phase III Double Blind, Placebo Controlled Study of Donepezil in Irradiated Brain Tumor Patients

COLON

CALGB 80702: A Phase III Trial of 6 versus 12 Treatments of Adjuvant FOLFOX plus Celecoxib or Placebo for Patients with Resected Stage III Colon Cancer

NCCTG N08CB: A Phase III Randomized, Placebo-Controlled Double Blind Study of Intravenous Calcium/Magnesium in Two Different Versions to Prevent Oxaliplatin-Induced Sensory Neuropathy

ESOPHAGEAL

Eli Lilly 14T- MC-JVBT: Randomized, Placeebo-Controlled, Double-Blind Phase 2 Study of Mfolfox6 Chemotherapy Plus Ramucirumab Drug Product versus Mfolfox6 Plus Placebo for Adavanced Adenocarcinomaof the Esophagus, Gastroesophageal Junction or Stomach

HEAD AND NECK

RTOG 0920: A Phase III study of Post Operative Radiation Therapy (IMRT) ± Cetuximab for Locally Advanced Resected Head and Neck Cancer

LUNG

E1505: A Phase III Randomized Trial of Adjuvant Chemotherapy With or Without Bevacizumab for Patients with Completely Resected Stage IB (≥4 cm)-IIIA Non-Small Cell Lung Cancer (NSCLC)

CALGB 30610: Phase III Comparison of Thoracic Radiotherapy Regimens in Patients With Limited Small Cell Lung Cancer Also Receiving Cisplatin and Etoposide

H3E-US-S130: Randomized, Open-Label, Phase 3 Study of Pemetrexed plus Carboplatin Followed by Maintenance Pemetrexed versus Paclitaxel plus Carboplatin and Bevacizumab Followed by Maintenance Bevacizumab in Patients with Advanced Non-Small Cell Lung Cancer of Nonsquamous Histology

PROSTATE

RTOG 0815: A Phase III Prospective Randomized Trial of Dose-Escalated Radiotherapy with or Without Short-Term Androgen Deprivation Therapy for Patients with Intermediate-Risk Prostate Cancer

RTOG 0831: A Randomized, Double-Blind, Placebo-Controlled Phase III Trial to Evaluate the Effectiveness of a Phosphodiesterase 5 Inhibitor, Tadalafil, In Prevention of Erectile Dysfunction in Patients Treated with Radiotherapy for Prostate Cancer

PREVENTON

I-ELCAP (International Early Lung Cancer Action Program): Early Detection of Lung Cancer Using Computed Tomography

Merck: A Phase III, Randomized, Placebo-Controlled, Clinical Trial to Study the Safety and Efficacy of V212 in Adult Patients with Solid Tumor or Hematologic Malignancy